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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5A' and Ligand = 'BDBM320417'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 5A


(Homo sapiens (Human))
BDBM320417
PNG
(2-[(3,5-difluorophenoxy)methyl]- 1H-pyrrolo[3,2-b]...)
Show SMILES OC(=O)c1ccnc2cc(COc3cc(F)cc(F)c3)[nH]c12
Show InChI InChI=1S/C15H10F2N2O3/c16-8-3-9(17)5-11(4-8)22-7-10-6-13-14(19-10)12(15(20)21)1-2-18-13/h1-6,19H,7H2,(H,20,21)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quantical Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...


US Patent US9738637 (2017)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))
BDBM320417
PNG
(2-[(3,5-difluorophenoxy)methyl]- 1H-pyrrolo[3,2-b]...)
Show SMILES OC(=O)c1ccnc2cc(COc3cc(F)cc(F)c3)[nH]c12
Show InChI InChI=1S/C15H10F2N2O3/c16-8-3-9(17)5-11(4-8)22-7-10-6-13-14(19-10)12(15(20)21)1-2-18-13/h1-6,19H,7H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...


US Patent US10174026 (2019)

More data for this
Ligand-Target Pair