BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5A' and Ligand = 'BDBM320421'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 5A


(Homo sapiens (Human))
BDBM320421
PNG
(2-(1-phenoxybutyl)-1H- pyrrolo[3,2-b]pyridine-7- c...)
Show SMILES CCCC(Oc1ccccc1)c1cc2nccc(C(O)=O)c2[nH]1
Show InChI InChI=1S/C18H18N2O3/c1-2-6-16(23-12-7-4-3-5-8-12)14-11-15-17(20-14)13(18(21)22)9-10-19-15/h3-5,7-11,16,20H,2,6H2,1H3,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quantical Research, Inc.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...


US Patent US9738637 (2017)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 5A


(Homo sapiens (Human))
BDBM320421
PNG
(2-(1-phenoxybutyl)-1H- pyrrolo[3,2-b]pyridine-7- c...)
Show SMILES CCCC(Oc1ccccc1)c1cc2nccc(C(O)=O)c2[nH]1
Show InChI InChI=1S/C18H18N2O3/c1-2-6-16(23-12-7-4-3-5-8-12)14-11-15-17(20-14)13(18(21)22)9-10-19-15/h3-5,7-11,16,20H,2,6H2,1H3,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...


US Patent US10174026 (2019)

More data for this
Ligand-Target Pair