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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM320423'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 5B


(Homo sapiens (Human))
BDBM320423
PNG
(2-[(2-chlorophenyl)-propoxy- methyl]-1H-pyrrolo[3,...)
Show SMILES CCCOC(c1cc2nccc(C(O)=O)c2[nH]1)c1ccccc1Cl
Show InChI InChI=1S/C18H17ClN2O3/c1-2-9-24-17(11-5-3-4-6-13(11)19)15-10-14-16(21-15)12(18(22)23)7-8-20-14/h3-8,10,17,21H,2,9H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
PDB
UniChem
Article
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...


US Patent US9738637 (2017)


Article DOI: 10.1021/jm030434f
BindingDB Entry DOI: 10.7270/Q2VD71K6
More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))
BDBM320423
PNG
(2-[(2-chlorophenyl)-propoxy- methyl]-1H-pyrrolo[3,...)
Show SMILES CCCOC(c1cc2nccc(C(O)=O)c2[nH]1)c1ccccc1Cl
Show InChI InChI=1S/C18H17ClN2O3/c1-2-9-24-17(11-5-3-4-6-13(11)19)15-10-14-16(21-15)12(18(22)23)7-8-20-14/h3-8,10,17,21H,2,9H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
PDB
UniChem
Article
US Patent
n/an/a<100n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...


US Patent US10174026 (2019)


Article DOI: 10.1016/j.bmcl.2005.04.028
BindingDB Entry DOI: 10.7270/Q2Z89FG4
More data for this
Ligand-Target Pair