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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM320426'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 5B


(Homo sapiens (Human))
BDBM320426
PNG
(2-[(4-methoxyphenoxy)methyl]- 1H-pyrrolo[3,2-b]pyr...)
Show SMILES COc1ccc(OCc2cc3nccc(C(O)=O)c3[nH]2)cc1
Show InChI InChI=1S/C16H14N2O4/c1-21-11-2-4-12(5-3-11)22-9-10-8-14-15(18-10)13(16(19)20)6-7-17-14/h2-8,18H,9H2,1H3,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...


US Patent US9738637 (2017)

More data for this
Ligand-Target Pair
Lysine-specific demethylase 5B


(Homo sapiens (Human))
BDBM320426
PNG
(2-[(4-methoxyphenoxy)methyl]- 1H-pyrrolo[3,2-b]pyr...)
Show SMILES COc1ccc(OCc2cc3nccc(C(O)=O)c3[nH]2)cc1
Show InChI InChI=1S/C16H14N2O4/c1-21-11-2-4-12(5-3-11)22-9-10-8-14-15(18-10)13(16(19)20)6-7-17-14/h2-8,18H,9H2,1H3,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...


US Patent US10174026 (2019)

More data for this
Ligand-Target Pair