Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5C' and Ligand = 'BDBM195612'
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM195612(GSK467)
Affinity DataIC50:  63nMAssay Description:Inhibition of KDM5C catalytic domain (1 -764 aa) (unknown origin) expressed in Sf9 cells using H3K4Me3 peptide as substrate by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM195612(GSK467)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of human KDM5C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM195612(GSK467)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of human KDM5C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM195612(GSK467)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of KDM5C (unknown origin) measured by by cell imaging assayMore data for this Ligand-Target Pair
In DepthDetails PubMed