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Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM194239'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM194239
PNG
(US10174030, Example 40 | US9670210, Example 40 6-{...)
Show SMILES COCC1(CN[C@@H]2CC2c2ccccc2)CCN(CC1)C(=O)c1ccc(N)nn1
Show InChI InChI=1S/C22H29N5O2/c1-29-15-22(14-24-19-13-17(19)16-5-3-2-4-6-16)9-11-27(12-10-22)21(28)18-7-8-20(23)26-25-18/h2-8,17,19,24H,9-15H2,1H3,(H2,23,26)/t17?,19-/m1/s1
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...


US Patent US10174030 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM194239
PNG
(US10174030, Example 40 | US9670210, Example 40 6-{...)
Show SMILES COCC1(CN[C@@H]2CC2c2ccccc2)CCN(CC1)C(=O)c1ccc(N)nn1
Show InChI InChI=1S/C22H29N5O2/c1-29-15-22(14-24-19-13-17(19)16-5-3-2-4-6-16)9-11-27(12-10-22)21(28)18-7-8-20(23)26-25-18/h2-8,17,19,24H,9-15H2,1H3,(H2,23,26)/t17?,19-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/a7.5n/a



Incyte Corporation

US Patent


Assay Description
LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...


US Patent US9670210 (2017)


BindingDB Entry DOI: 10.7270/Q2H1306F
More data for this
Ligand-Target Pair