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Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM194713'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM194713
PNG
(US10174030, Example 99 | US9670210, Example 99 1-{...)
Show SMILES COc1ccc(CC2(CN[C@@H]3CC3c3ccccc3)CCN(CC3(CCC3)C(O)=O)CC2)cc1
Show InChI InChI=1S/C29H38N2O3/c1-34-24-10-8-22(9-11-24)19-28(20-30-26-18-25(26)23-6-3-2-4-7-23)14-16-31(17-15-28)21-29(27(32)33)12-5-13-29/h2-4,6-11,25-26,30H,5,12-21H2,1H3,(H,32,33)/t25?,26-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...


US Patent US10174030 (2019)

More data for this
Ligand-Target Pair
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM194713
PNG
(US10174030, Example 99 | US9670210, Example 99 1-{...)
Show SMILES COc1ccc(CC2(CN[C@@H]3CC3c3ccccc3)CCN(CC3(CCC3)C(O)=O)CC2)cc1
Show InChI InChI=1S/C29H38N2O3/c1-34-24-10-8-22(9-11-24)19-28(20-30-26-18-25(26)23-6-3-2-4-7-23)14-16-31(17-15-28)21-29(27(32)33)12-5-13-29/h2-4,6-11,25-26,30H,5,12-21H2,1H3,(H,32,33)/t25?,26-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/a7.5n/a



Incyte Corporation

US Patent


Assay Description
LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...


US Patent US9670210 (2017)


BindingDB Entry DOI: 10.7270/Q2H1306F
More data for this
Ligand-Target Pair