BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM340063'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM340063
PNG
(2-fluoro-4-{5-(4-methylphenyl)-8-[(3R)-pyrrolidin-...)
Show SMILES Cc1ccc(cc1)-c1c(cc(OC[C@@H]2CCN(C2)C(=O)OC(C)(C)C)c2nncn12)-c1ccc(C#N)c(F)c1
Show InChI InChI=1S/C30H30FN5O3/c1-19-5-7-21(8-6-19)27-24(22-9-10-23(15-32)25(31)13-22)14-26(28-34-33-18-36(27)28)38-17-20-11-12-35(16-20)29(37)39-30(2,3)4/h5-10,13-14,18,20H,11-12,16-17H2,1-4H3/t20-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<50n/an/an/an/an/an/a



Incyte Corporation

US Patent


Assay Description
LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...


US Patent US9758523 (2017)

More data for this
Ligand-Target Pair