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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM369498'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM369498
PNG
(Synthesis of Intermediate 79: tert-butyl ((1R, 2S)...)
Show SMILES FC(F)(F)C(=O)N1CCC(CC1)N[C@@H]1C[C@H]1c1ccccc1
Show InChI InChI=1/C16H19F3N2O/c17-16(18,19)15(22)21-8-6-12(7-9-21)20-14-10-13(14)11-4-2-1-3-5-11/h1-5,12-14,20H,6-10H2/t13-,14+/s2
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 33n/an/an/an/an/an/a



MIRATI THERAPEUTICS, INC.

US Patent


Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...


US Patent US10233152 (2019)

More data for this
Ligand-Target Pair