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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM369561'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM369561
PNG
(US10233152, Example 78)
Show SMILES O=C1CCCCN1c1ccc(OCCN2CC(CN[C@@H]3C[C@H]3c3ccccc3)C2)cc1
Show InChI InChI=1/C26H33N3O2/c30-26-8-4-5-13-29(26)22-9-11-23(12-10-22)31-15-14-28-18-20(19-28)17-27-25-16-24(25)21-6-2-1-3-7-21/h1-3,6-7,9-12,20,24-25,27H,4-5,8,13-19H2/t24-,25+/s2
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 7n/an/an/an/an/an/a



MIRATI THERAPEUTICS, INC.

US Patent


Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...


US Patent US10233152 (2019)

More data for this
Ligand-Target Pair