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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM369566'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM369566
PNG
(US10233152, Example 81)
Show SMILES CN1CCN(CC1)c1ccc(OCCN2CC(CN[C@@H]3C[C@H]3c3ccccc3)C2)cc1
Show InChI InChI=1/C26H36N4O/c1-28-11-13-30(14-12-28)23-7-9-24(10-8-23)31-16-15-29-19-21(20-29)18-27-26-17-25(26)22-5-3-2-4-6-22/h2-10,21,25-27H,11-20H2,1H3/t25-,26+/s2
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/an/an/a



MIRATI THERAPEUTICS, INC.

US Patent


Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...


US Patent US10233152 (2019)

More data for this
Ligand-Target Pair