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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM369570'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM369570
PNG
(US10233152, Example 85)
Show SMILES Cc1ccc(OCCN2CCC(CC2)N[C@@H]2C[C@H]2c2ccccc2)cn1
Show InChI InChI=1/C22H29N3O/c1-17-7-8-20(16-23-17)26-14-13-25-11-9-19(10-12-25)24-22-15-21(22)18-5-3-2-4-6-18/h2-8,16,19,21-22,24H,9-15H2,1H3/t21-,22+/s2
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



MIRATI THERAPEUTICS, INC.

US Patent


Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...


US Patent US10233152 (2019)

More data for this
Ligand-Target Pair