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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysophosphatidic acid receptor 1' and Ligand = 'BDBM251723'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM251723
PNG
(US10100018, Example 59 | US9464060, 59)
Show SMILES COc1cccc(CN(Cc2ccc(C(O)=O)c(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)c1
Show InChI InChI=1S/C29H23F2NO5/c1-36-23-6-4-5-19(15-23)17-32(18-20-9-14-24(29(34)35)26(31)16-20)28(33)21-10-12-22(13-11-21)37-27-8-3-2-7-25(27)30/h2-16H,17-18H2,1H3,(H,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/a25



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...


US Patent US10100018 (2018)

More data for this
Ligand-Target Pair