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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysophosphatidic acid receptor Edg-4' and Ligand = 'BDBM50373819'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysophosphatidic acid receptor Edg-4


(Homo sapiens (Human))
BDBM50373819
PNG
(CHEMBL402218)
Show SMILES CC(CN1CCN(CC1)c1ccc(F)cc1)Nc1nc(nc2ccccc12)C1CC1
Show InChI InChI=1S/C24H28FN5/c1-17(16-29-12-14-30(15-13-29)20-10-8-19(25)9-11-20)26-24-21-4-2-3-5-22(21)27-23(28-24)18-6-7-18/h2-5,8-11,17-18H,6-7,12-16H2,1H3,(H,26,27,28)
NCI pathway
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at LPA2 assessed as inhibition of LPA-induced Ca2+ flux


Bioorg Med Chem Lett 18: 1037-41 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.024
BindingDB Entry DOI: 10.7270/Q2JQ11W8
More data for this
Ligand-Target Pair