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Found 2 Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM50344708'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344708((R)-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimi...)
Affinity DataEC50:  129nMAssay Description:Inhibition of MK2 pretreated for 30 mins before fluorescein labeled substrate peptide addition measured after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344708((R)-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of MK2 in LPS-stimulated human THP1 cells assessed as inhibition of Hsp27 phosphorylation pretreated 60 mins before LPS challenge measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed