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Found 2 Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM50380292'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380292(CHEMBL2017446)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of MK2 using Acam peptide as substrate incubated for 30 mins prior to substrate addition measured after 10 mins using 100 uM ATP by DELFIA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380292(CHEMBL2017446)
Affinity DataEC50: >7.70E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation in IL-1beta stimulated human SW1353 cells incubated for 30 mins prior to IL-1beta-stimulation measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed