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Found 2 Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM181400'
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM181400(US9139577, 2.008 | US9708274, 2.008)
Affinity DataIC50:  25nMpH: 7.5Assay Description:The inhibition of kinase activity of MNK1a was assessed using pre-activated GST-MNK1a. The 2xMKNK1 (MNK1) mixture is prepared in 50 mM HEPES pH 7.5, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Evotec International

US Patent
LigandPNGBDBM181400(US9139577, 2.008 | US9708274, 2.008)
Affinity DataIC50:  25nMAssay Description:The Z-LYTE biochemical assay employs a fluorescence-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated and n...More data for this Ligand-Target Pair
In DepthDetails US Patent