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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1)' and Ligand = 'BDBM223050'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1)


(Homo sapiens (Human))
BDBM223050
PNG
(US9320737, IV.8)
Show SMILES CS(=O)(CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC#N
Show InChI InChI=1S/C19H17N5O3S/c1-28(25,22-13-20)10-4-9-26-19-8-7-18-21-12-15(24(18)23-19)17-11-14-5-2-3-6-16(14)27-17/h2-3,5-8,11-12H,4,9-10H2,1H3
PDB

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/a7.522



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
For the assay 50 mL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...


US Patent US9320737 (2016)


BindingDB Entry DOI: 10.7270/Q22V2F00
More data for this
Ligand-Target Pair