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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM346163'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346163
PNG
(US10202370, Example 113 | [2-(3-Difluoromethyl- ph...)
Show SMILES Cc1cc2nc(-c3cccc(c3)C(F)F)n(C)c2cc1Nc1nc(cs1)-c1cccnc1
Show InChI InChI=1S/C24H19F2N5S/c1-14-9-19-21(31(2)23(28-19)16-6-3-5-15(10-16)22(25)26)11-18(14)29-24-30-20(13-32-24)17-7-4-8-27-12-17/h3-13,22H,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.50E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair