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Found 3 Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM445949'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445949(US10669246, Example 1 | US10968188, Example 1)
Affinity DataKi: >1.00E+4nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445949(US10669246, Example 1 | US10968188, Example 1)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of recombinant human c-Kit assessed as luminescence using poly (4:1 Glu, Tyr) peptide as substrate incubated for 2 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445949(US10669246, Example 1 | US10968188, Example 1)
Affinity DataIC50: >1.00E+4nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), Manganese(II) chloride (MnCl2), Bovine serum albumin (BSA) and dimethylsulf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent