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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix M2-1' and Ligand = 'BDBM324649'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix M2-1


(Human respiratory syncytial virus A (strain A2))
BDBM324649
PNG
(1'-({5-Methyl-1-[2- (methylsulfonyl)ethyl]-1H-indo...)
Show SMILES Cc1ccc2n(CCS(C)(=O)=O)c(CN3C(=O)C4(CC4)c4ccncc34)cc2c1
Show InChI InChI=1S/C22H23N3O3S/c1-15-3-4-19-16(11-15)12-17(24(19)9-10-29(2,27)28)14-25-20-13-23-8-5-18(20)22(6-7-22)21(25)26/h3-5,8,11-13H,6-7,9-10,14H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 9n/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
To measure anti-RSV activity of compounds, 96-well plates are seeded with 6103 cells per well in Dulbecco's modified Eagle's medium (DMEM) c...


US Patent US10189838 (2019)

More data for this
Ligand-Target Pair