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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-2 (MMP-2)' and Ligand = 'BDBM199120'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-2 (MMP-2)


(Rattus norvegicus (Rat))
BDBM199120
PNG
(N-(4-(1-(4,6-bis(ethylamino)-1,3,5-triazin-2-yl)-5...)
Show SMILES CCNc1nc(NCC)nc(n1)-n1nc(cc1-c1ccc(OC)cc1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C30H32N8O3S/c1-5-31-28-33-29(32-6-2)35-30(34-28)38-27(22-11-15-24(39-4)16-12-22)19-26(36-38)21-9-13-23(14-10-21)37-40-41-42-25-17-7-20(3)8-18-25/h7-19,37H,5-6H2,1-4H3,(H2,31,32,33,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 332n/an/an/an/a7.525



Zhejiang Hospital



Assay Description
where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...


Chem Biol Drug Des 88: 756-765 (2016)


Article DOI: 10.1111/cbdd.12807
BindingDB Entry DOI: 10.7270/Q2ZW1JR4
More data for this
Ligand-Target Pair