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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-2 (MMP-2)' and Ligand = 'BDBM199123'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-2 (MMP-2)


(Rattus norvegicus (Rat))
BDBM199123
PNG
(N-(4-(1-(4,6-bis((4-hydroxyphenyl)amino)-1,3,5-tri...)
Show SMILES COc1ccc(cc1)-c1cc(nn1-c1nc(Nc2ccc(O)cc2)nc(Nc2ccc(O)cc2)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C38H32N8O5S/c1-24-3-21-33(22-4-24)52-51-50-45-29-9-5-25(6-10-29)34-23-35(26-7-19-32(49-2)20-8-26)46(44-34)38-42-36(39-27-11-15-30(47)16-12-27)41-37(43-38)40-28-13-17-31(48)18-14-28/h3-23,45,47-48H,1-2H3,(H2,39,40,41,42,43)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.12n/an/an/an/an/an/a



Zhejiang Hospital



Assay Description
where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...


Chem Biol Drug Des 88: 756-765 (2016)

More data for this
Ligand-Target Pair