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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-2 (MMP-2)' and Ligand = 'BDBM199124'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-2 (MMP-2)


(Rattus norvegicus (Rat))
BDBM199124
PNG
(N-(4-(1-(4,6-bis((4-methoxyphenyl)amino)-1,3,5-tri...)
Show SMILES COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(n2)-n2nc(cc2-c2ccc(OC)cc2)-c2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2)cc1
Show InChI InChI=1S/C40H36N8O5S/c1-26-5-23-35(24-6-26)54-53-52-47-31-11-7-27(8-12-31)36-25-37(28-9-17-32(49-2)18-10-28)48(46-36)40-44-38(41-29-13-19-33(50-3)20-14-29)43-39(45-40)42-30-15-21-34(51-4)22-16-30/h5-25,47H,1-4H3,(H2,41,42,43,44,45)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 18.6n/an/an/an/a7.525



Zhejiang Hospital



Assay Description
where a pro-fluorescing peptide is used as substrate, and the fluorogenic activity of its cleavage product is measured after co-incubation with the a...


Chem Biol Drug Des 88: 756-765 (2016)


Article DOI: 10.1111/cbdd.12807
BindingDB Entry DOI: 10.7270/Q2ZW1JR4
More data for this
Ligand-Target Pair