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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-7 (MMP7)' and Ligand = 'BDBM50208340'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-7 (MMP7)


(Homo sapiens (Human))
BDBM50208340
PNG
(4-((2-methylquinolin-4-yl)methoxy)-N-(2-(2-oxo-2,3...)
Show SMILES Cc1cc(COc2ccc(cc2)C(=O)Nc2ccccc2C(=O)c2c[nH]c(=O)[nH]2)c2ccccc2n1
Show InChI InChI=1S/C28H22N4O4/c1-17-14-19(21-6-2-4-8-23(21)30-17)16-36-20-12-10-18(11-13-20)27(34)31-24-9-5-3-7-22(24)26(33)25-15-29-28(35)32-25/h2-15H,16H2,1H3,(H,31,34)(H2,29,32,35)
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PC cid
PC sid
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Article
PubMed
>636n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of MMP7


Bioorg Med Chem 16: 8781-94 (2008)


Article DOI: 10.1016/j.bmc.2008.08.058
BindingDB Entry DOI: 10.7270/Q2JD4WM2
More data for this
Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7)


(Homo sapiens (Human))
BDBM50208340
PNG
(4-((2-methylquinolin-4-yl)methoxy)-N-(2-(2-oxo-2,3...)
Show SMILES Cc1cc(COc2ccc(cc2)C(=O)Nc2ccccc2C(=O)c2c[nH]c(=O)[nH]2)c2ccccc2n1
Show InChI InChI=1S/C28H22N4O4/c1-17-14-19(21-6-2-4-8-23(21)30-17)16-36-20-12-10-18(11-13-20)27(34)31-24-9-5-3-7-22(24)26(33)25-15-29-28(35)32-25/h2-15H,16H2,1H3,(H,31,34)(H2,29,32,35)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>6.37E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to MMP7


Bioorg Med Chem Lett 17: 2769-74 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.076
BindingDB Entry DOI: 10.7270/Q2ZC82J4
More data for this
Ligand-Target Pair