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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor' and Ligand = 'BDBM50199235'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (human))
BDBM50199235
PNG
(6-(4-chlorophenyl)-3-[2-({4-[4-(trifluoromethyl)ph...)
Show SMILES FC(F)(F)c1ccc(cc1)C1CCN(Cc2ccc3cc(ccc3n2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C34H26ClF3N4OS/c35-26-8-3-23(4-9-26)31-18-30-32(44-31)33(43)42(20-39-30)28-11-12-29-24(17-28)5-10-27(40-29)19-41-15-13-22(14-16-41)21-1-6-25(7-2-21)34(36,37)38/h1-12,17-18,20,22H,13-16,19H2
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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6.10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay


J Med Chem 49: 7095-107 (2006)


Article DOI: 10.1021/jm060572f
BindingDB Entry DOI: 10.7270/Q2P26XS8
More data for this
Ligand-Target Pair