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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 3' and Ligand = 'BDBM50122063'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 3


(Mus musculus)
BDBM50122063
PNG
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O
Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.34E+4n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells


J Med Chem 45: 5736-44 (2002)


Article DOI: 10.1021/jm020296e
BindingDB Entry DOI: 10.7270/Q2Q2410R
More data for this
Ligand-Target Pair