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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM160183'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160183
PNG
(US9040663, 29)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](CCN)NC1=O)C(N)=O
Show InChI InChI=1S/C54H75N17O9/c1-31(72)65-39(15-8-26-62-53(57)58)47(75)68-41-21-22-45(73)61-25-7-14-38(46(56)74)66-52(80)44(29-35-30-64-37-13-6-5-12-36(35)37)71-48(76)40(16-9-27-63-54(59)60)67-51(79)43(70-50(78)42(23-24-55)69-49(41)77)28-32-17-19-34(20-18-32)33-10-3-2-4-11-33/h2-6,10-13,17-20,30,38-44,64H,7-9,14-16,21-29,55H2,1H3,(H2,56,74)(H,61,73)(H,65,72)(H,66,80)(H,67,79)(H,68,75)(H,69,77)(H,70,78)(H,71,76)(H4,57,58,62)(H4,59,60,63)/t38-,39-,40-,41-,42-,43+,44-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
0.5 -55.2n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair