Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50136357'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136357(CHEMBL341982 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataIC50:  10nMAssay Description:Binding activity was measured using membranes of Hi5 cells expressing the human MC4R receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136357(CHEMBL341982 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against cAMP release in CHO cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136357(CHEMBL341982 | N-[(R)-1-(4-Chloro-benzyl)-2-(4-cyc...)
Affinity DataEC50:  40nMAssay Description:Stimulation of adenylate cyclase in HEK293 cells expressing the human MC4R receptor was determined by measuring cAMP accumulation using the RPA559 SP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed