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Found 6 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50136518'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136518((3R,4S)-4-Phenyl-pyrrolidine-3-carboxylic acid {(R...)
Affinity DataIC50:  98nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136518((3R,4S)-4-Phenyl-pyrrolidine-3-carboxylic acid {(R...)
Affinity DataIC50:  190nMAssay Description:Concentration required to inhibit binding of [125I]-NDP-alpha-MSH from membranes prepared from CHO cells expressing human melanocortin subtype-4-rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136518((3R,4S)-4-Phenyl-pyrrolidine-3-carboxylic acid {(R...)
Affinity DataIC50:  380nMAssay Description:Effective concentration for cAMP accumulation relative to alpha-MSH at human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136518((3R,4S)-4-Phenyl-pyrrolidine-3-carboxylic acid {(R...)
Affinity DataEC50:  400nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136518((3R,4S)-4-Phenyl-pyrrolidine-3-carboxylic acid {(R...)
Affinity DataEC50:  405nMAssay Description:Effective concentration for cAMP accumulation relative to alpha-MSH at human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136518((3R,4S)-4-Phenyl-pyrrolidine-3-carboxylic acid {(R...)
Affinity DataEC50:  250nMAssay Description:Concentration required to inhibit binding of [125I]-NDP-alpha-MSH from membranes prepared from CHO cells expressing human melanocortin subtype-4-rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed