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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 5 (MC5R)' and Ligand = 'BDBM50150835'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50150835
PNG
(4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-...)
Show SMILES CC(C)(N)CNC(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1
Show InChI InChI=1S/C26H35Cl2N5O/c1-26(2,29)17-31-25(32-21-6-4-3-5-7-21)33-22-12-9-19(10-13-22)24(34)30-15-14-18-8-11-20(27)16-23(18)28/h8-13,16,21H,3-7,14-15,17,29H2,1-2H3,(H,30,34)(H2,31,32,33)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.30n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK-293 cells


J Med Chem 47: 4083-8 (2004)


Article DOI: 10.1021/jm0400496
BindingDB Entry DOI: 10.7270/Q2JH3KM0
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50150835
PNG
(4-[N''-(2-Amino-2-methyl-propyl)-N''''-cyclohexyl-...)
Show SMILES CC(C)(N)CNC(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1
Show InChI InChI=1S/C26H35Cl2N5O/c1-26(2,29)17-31-25(32-21-6-4-3-5-7-21)33-22-12-9-19(10-13-22)24(34)30-15-14-18-8-11-20(27)16-23(18)28/h8-13,16,21H,3-7,14-15,17,29H2,1-2H3,(H,30,34)(H2,31,32,33)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 530n/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK293 cells


J Med Chem 47: 4083-8 (2004)


Article DOI: 10.1021/jm0400496
BindingDB Entry DOI: 10.7270/Q2JH3KM0
More data for this
Ligand-Target Pair