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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 5 (MC5R)' and Ligand = 'BDBM50358565'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50358565
PNG
(CHEMBL1923668)
Show SMILES CCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCCCNC(=O)CCCC#C)C(C)C)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O
Show InChI InChI=1S/C89H121N23O17/c1-5-7-11-32-73(115)97-39-19-18-28-62(90)77(119)107-68(45-56-34-37-61(113)38-35-56)86(128)112-76(53(3)4)87(129)106-63(29-8-6-2)78(120)101-51-74(116)103-70(47-60-49-96-52-102-60)84(126)110-69(46-57-33-36-58-26-16-17-27-59(58)42-57)82(124)104-65(31-21-41-99-89(94)95)81(123)109-67(44-55-24-14-10-15-25-55)83(125)111-71(48-75(117)118)85(127)105-64(30-20-40-98-88(92)93)80(122)108-66(79(121)100-50-72(91)114)43-54-22-12-9-13-23-54/h1,9-10,12-17,22-27,33-38,42,49,52-53,62-71,76,113H,6-8,11,18-21,28-32,39-41,43-48,50-51,90H2,2-4H3,(H2,91,114)(H,96,102)(H,97,115)(H,100,121)(H,101,120)(H,103,116)(H,104,124)(H,105,127)(H,106,129)(H,107,119)(H,108,122)(H,109,123)(H,110,126)(H,111,125)(H,112,128)(H,117,118)(H4,92,93,98)(H4,94,95,99)/t62-,63-,64-,65-,66-,67+,68-,69+,70-,71-,76-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.90n/an/an/an/an/an/an/an/a



H. Lee Moffitt Cancer Center& Research Institute

Curated by ChEMBL


Assay Description
Displacement of Eu-NDP-alphaMSH from human MC5 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysis


J Med Chem 54: 8078-84 (2011)


Article DOI: 10.1021/jm201226w
BindingDB Entry DOI: 10.7270/Q2G1618K
More data for this
Ligand-Target Pair