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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM160615'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM160615
PNG
(US9682980, 8-Chloro-3-(cyclopropylmethyl)-N-(((1R,...)
Show SMILES Cc1c(NC[C@@H]2C[C@@H]2c2ccc(F)cc2)cnn2c(CC3CC3)nnc12
Show InChI InChI=1S/C20H22FN5/c1-12-18(11-23-26-19(8-13-2-3-13)24-25-20(12)26)22-10-15-9-17(15)14-4-6-16(21)7-5-14/h4-7,11,13,15,17,22H,2-3,8-10H2,1H3/t15-,17+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 158n/an/a7.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...


US Patent US9682980 (2017)


BindingDB Entry DOI: 10.7270/Q2J964JS
More data for this
Ligand-Target Pair