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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM160721'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM160721
PNG
(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(py...)
Show SMILES Clc1c(cnn2c(CC3CC3)nnc12)N1CCC(CC1)c1ncccn1
Show InChI InChI=1S/C18H20ClN7/c19-16-14(11-22-26-15(10-12-2-3-12)23-24-18(16)26)25-8-4-13(5-9-25)17-20-6-1-7-21-17/h1,6-7,11-13H,2-5,8-10H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 280n/an/a7.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...


US Patent US9682980 (2017)


BindingDB Entry DOI: 10.7270/Q2J964JS
More data for this
Ligand-Target Pair