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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM160725'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM160725
PNG
(US9682980, 8-Chloro-7-(4-(4-fluorophenyl)piperidin...)
Show SMILES CC(C)(C)Cc1nnc2c(Cl)c(cnn12)N1CCC(CC1)c1ccc(F)cc1
Show InChI InChI=1S/C21H25ClFN5/c1-21(2,3)12-18-25-26-20-19(22)17(13-24-28(18)20)27-10-8-15(9-11-27)14-4-6-16(23)7-5-14/h4-7,13,15H,8-12H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 145n/an/a7.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...


US Patent US9682980 (2017)


BindingDB Entry DOI: 10.7270/Q2J964JS
More data for this
Ligand-Target Pair