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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM160729'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM160729
PNG
(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(spiro...)
Show SMILES Clc1c(cnn2c(CC3CC3)nnc12)N1CCC2(CC1)C=Cc1ccccc21
Show InChI InChI=1S/C22H22ClN5/c23-20-18(14-24-28-19(13-15-5-6-15)25-26-21(20)28)27-11-9-22(10-12-27)8-7-16-3-1-2-4-17(16)22/h1-4,7-8,14-15H,5-6,9-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 145n/an/a7.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...


US Patent US9682980 (2017)


BindingDB Entry DOI: 10.7270/Q2J964JS
More data for this
Ligand-Target Pair