BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM160815'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM160815
PNG
(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(3-...)
Show SMILES FC(F)(F)c1cccc(n1)C1CCN(CC1)c1cnn2c(CC3CC3)nnc2c1Cl
Show InChI InChI=1S/C20H20ClF3N6/c21-18-15(11-25-30-17(10-12-4-5-12)27-28-19(18)30)29-8-6-13(7-9-29)14-2-1-3-16(26-14)20(22,23)24/h1-3,11-13H,4-10H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 34n/an/a7.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...


US Patent US9682980 (2017)


BindingDB Entry DOI: 10.7270/Q2J964JS
More data for this
Ligand-Target Pair