Found 8 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50034503'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataKi: 110nMAssay Description:Binding affinity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataEC50: 300nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataEC50: 350nMAssay Description:Agonist activity at rat mGlu2 receptor by FRET based mGlu sensor assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataEC50: 45nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by PDSP Ki Database
F. Hoffmann-La Roche
Curated by PDSP Ki Database
Affinity DataEC50: 300nMAssay Description:Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair