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Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50207400'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as increase in intracellular calcium l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50:  201nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed