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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50372868'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50372868(CHEMBL404886)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at rat mGluR2 assessed as effect on (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50372868(CHEMBL404886)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]LY354740 from rat recombinant mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed