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Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM361358'
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM361358(6-((1H-pyrazolo[4,3-b] pyridin-3- yl)amino)-N-(3,3...)
Affinity DataEC50:  164nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM361358(6-((1H-pyrazolo[4,3-b] pyridin-3- yl)amino)-N-(3,3...)
Affinity DataEC50:  68nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM361358(6-((1H-pyrazolo[4,3-b] pyridin-3- yl)amino)-N-(3,3...)
Affinity DataEC50:  68nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed