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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM361376'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM361376
PNG
((6-((1H-pyrazolo[3,4-b] pyrazin-3- yl)amino)benzo[...)
Show SMILES FC1(F)CCN(CC1)C(=O)c1nsc2cc(Nc3n[nH]c4nccnc34)ccc12
Show InChI InChI=1S/C18H15F2N7OS/c19-18(20)3-7-27(8-4-18)17(28)13-11-2-1-10(9-12(11)29-26-13)23-16-14-15(24-25-16)22-6-5-21-14/h1-2,5-6,9H,3-4,7-8H2,(H2,22,23,24,25)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 827n/an/an/an/a



Vanderbilt University

US Patent


Assay Description
In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...


US Patent US10221172 (2019)


Article DOI: 10.1021/jm070728r
More data for this
Ligand-Target Pair