Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM135979'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM135979(US8853203, 33 | US9650377, Example 33)
Affinity DataIC50:  13nMAssay Description:Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM135979(US8853203, 33 | US9650377, Example 33)
Affinity DataIC50:  13nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair
In DepthDetails US Patent