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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM136034'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM136034(US8853203, 88a | US9650377, Example 88a)
Affinity DataIC50:  5nMAssay Description:Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM136034(US8853203, 88a | US9650377, Example 88a)
Affinity DataIC50:  5nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair
In DepthDetails US Patent