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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM196508'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM196508(US9212165, 16)
Affinity DataKi:  4.5nM ΔG°:  -47.6kJ/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM196508(US9212165, 16)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The rmGluR5 or hmGluR5 was stably expressed in a HEK 293 cell line and gown in Dulbecco's Modified Eagle Medium (DMEM) (Invitrogen, Carlsbad, Cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent