Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50342460'
Affinity DataKi: 182nMAssay Description:Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Negative allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Allosteric modulation of mGluR5 in E17 rat neuronal cultures assessed as inhibition of (S)-3,5-dihydroxyphenylglycine-induced calcium levelMore data for this Ligand-Target Pair