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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50344398'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50344398(6-cyclopentyl-2-(m-tolylethynyl)-7,8-dihydro-1,6-n...)
Affinity DataKi:  670nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50344398(6-cyclopentyl-2-(m-tolylethynyl)-7,8-dihydro-1,6-n...)
Affinity DataEC50:  7.5nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as increase of L-glutamate-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed