Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 8' and Ligand = 'BDBM50138783'
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  31nMAssay Description:Metabotropic glutamate receptor 8 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  31nMAssay Description:Activation of human metabotropic glutamate 8 receptor expressed in golden hamster AV12-664 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50138783(4-((S)-Amino-carboxy-methyl)-phthalic acid | 4-[am...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at mGlu8 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair