Found 5 Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein tau' and Ligand = 'BDBM50241461'
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of His-tagged human brain tau 3R MBD aggregation after 16 hrs by thioflavin T fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human full length recombinant tau-441 expressed in Escherichia coli assessed as inhibition of heparin-induced protein aggregation by me...More data for this Ligand-Target Pair
Affinity DataEC50: 590nMAssay Description:Inhibition of tau aggregation (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of tau-tau binding (unknown origin) assessed as increase in dissolved paired helical filamentsMore data for this Ligand-Target Pair