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Found 1 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM157163'
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM157163(US9023865, 8)
Affinity DataIC50:  0.516nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
In DepthDetails US Patent